Age-Related Macular Degeneration (AMD)

What is the macula?

The macula is the central area of the retina responsible for central vision. It makes up only a small part of the retina, yet it is much more sensitive to detail than the rest of the retina (called the peripheral retina). The macula allows you to do things like thread a needle, read small print, and read street signs, whilst the peripheral retina gives you side vision.

What is AMD?

Age-Related Macular Degeneration or AMD is a retinal eye disease that causes progressive loss of central vision whilst leaving the peripheral vision intact.  This progressive degeneration affects the macula, hence it makes it difficult to do things like read, drive, write, recognise faces and perform daily tasks.

AMD can be divided into two general types:

  • Dry (Atrophic): it results from a slow wearing away of the layers of the macula, and occurs over many years. As dry AMD progresses, you may notice central blurring or distortion in your vision.  With dry AMD, vision loss is usually gradual and people who develop it must carefully and constantly monitor their central vision, partly because the dry form can change into the more damaging form of macular degeneration known as wet AMD.

 

  • Wet (Exudative): it is due to leakage of blood or fluid from abnormal blood vessel growth into the dry AMD and it can cause damage more quickly to your central vision than the dry form of AMD. The blood vessel growth is called choroidal neovascularisation (CNV) because the vessels come from the choroid (the blood vessel layer under the retina) and the longer these abnormal vessels leak or grow, the higher the risk of losing detailed vision. Therefore wet AMD generally leads to sudden distortion or loss of central vision within a short period of time.

 

What are the symptoms?

With macular degeneration, you may have symptoms such as blurriness or dark areas or distortion in your central vision, and perhaps permanent loss of your central vision. It usually does not affect peripheral vision. A change in colour vision may also occur as the macula is the part of the retina responsible for colour vision.

Many people are not aware that they have the disease until they have a noticeable vision problem or until it is discovered during an eye examination.

Who is at risk?

The risk of AMD increases as a person gets older, with one in seven people over the age of 50 developing AMD. Genetics also play an important role; hence people with a family history of AMD are at a higher risk of getting the disease.  Smoking is a significant risk factor for developing AMD.

 

How is the condition diagnosed?

Due to the fact that most AMD cases go undetected until significant changes have occurred, regular eye exams by an eye health professional can be of great help for early detection. In addition, checking your own eyes weekly with an Amsler grid is important for early detection of AMD.

Dr Hilford will undertake a dilated examination of your eyes and tests such as optical coherence tomography (OCT) and/or fluorescein angiography will be required.

What are the treatment options? Currently there is no curative treatment for dry AMD.  However, there are various ways to help slow down the progression of dry AMD.
  • Cessation of smoking (if applicable).
  • Eat a diet rich in fresh fruit and green, leafy vegetables
  • Increase intake of fish and other omega rich foods.
  • Macular supplements (if applicable)
  • Wear ultraviolet protection when outdoors.
  • Monitor vision with the Amsler grid.
  • Routine comprehensive eye exams
Treating wet AMD normally involves the use of anti-VEGF treatment via intravitreal injections. Dr Hilford will discuss injection types and treatment regimes based on your therapeutic needs.

Retinal Vein Occlusion

What is the retina?

The retina is the light-sensitive nerve tissue lining the back of the eye (“the film in the camera”).The retina is nourished by blood flow, which provides nutrients and oxygen that nerve cells need. A healthy, intact retina is the key to clear vision.

What is a retinal vein occlusion?

A retinal vein occlusion means that a vein in the retinal circulation has become blocked.

Retinal veins carry blood from the retina back to the heart for re-circulation.  If one of these veins becomes blocked a pressure build up causes the walls of the vein to leak blood and excess fluid into the retina. When this fluid collects in the macula (the central area of the retina responsible for central vision), vision becomes blurry.

There are two types of retinal vein occlusions

  • Branch Retinal Vein Occlusion (BRVO): it happens when a smaller branch of the main retinal vein is blocked, damaging the area of the retina drained by this branch. Visual loss can happen but usually not as severely as a blockage of the main retinal vein (see below).
  • Central Retinal Vein Occlusion (CRVO): it is caused by a blockage of the main retinal vein resulting in poor blood flow throughout the whole retina which can translate to severe vision loss.

What are the symptoms?

The most common symptom is vision loss or blurring in part or all of one eye. The symptoms may happen suddenly or become worse over several hours or days. Sometimes there is a sudden and complete loss of vision.

Pain in the eye can occur as a complication of a central retinal vein occlusion.  This is caused by excessive eye pressure called neovascular glaucoma. This normally occurs a few months after a severe CRVO which has gone untreated.

 

Who is at risk?

Retinal vein occlusions are more common in:

  • People over 65 years of age
  • High blood pressure
  • High cholesterol levels
  • Diabetes
  • People who smoke
  • Glaucoma
  • Some blood disorders

How is the condition diagnosed?

Dr Hilford will undertake a dilated examination of your eyes and tests such as optical coherence tomography (OCT) and/or fluorescein angiography will be required.

What are the treatment options?

Dr Hilford will discuss the treatment options that are available which include intravitreal injections and/or laser treatment.

Retinal Artery Occlusion

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